Electron microscopy

In electron microscopy, we offer

  • 3D SEM-FIB acquisition,
  • high resolution scanning electron microscopy on embedded, dried or frozen samples,
  • elemental analysis (EDS),
  • combined light and electron microscopy (CLEM).

We also offer a wide range of sample preparation methods:

  • standard chemical fixation (without consultation after completing  the application form),
  • high pressure freezing (HPF) follow by cryosubstitution (AFS),
  • preparing of ultrathin sections for TEM,
  • sample prep for SEM,
  • immunolabeling,
  • optimized preparation procedures after consultation.


We acknowledge Imaging Methods Core Facility at BIOCEV, institution supported by the MEYS CR (Large RI Project LM2018129 Czech-BioImaging) and ERDF (project No. CZ.02.1.01/0.0/0.0/18_046/0016045) for their support with obtaining imaging data presented in this paper.